Sign up for e-mail updates on the latest coronavirus news and researchĪ preliminary study that mixed and matched vaccines in the United States found that people who got J&J as their first dose developed much higher levels of antibodies if their second dose was an mRNA vaccine than if it was another jab of J&J. But AstraZeneca followed by Pfizer was 67 percent effective and AstraZeneca boosted with Moderna was 79 effective, researchers reported October 18 in the Lancet Regional Health – Europe. Studies show combining AstraZeneca’s COVID-19 vaccine with a boost from the Pfizer shot (or sometimes Moderna) was more effective than getting another dose of AstraZeneca.įor instance, in Sweden, a double dose of AstraZeneca was about 50 percent effective at preventing symptomatic illness. Both vaccines use adenoviruses to deliver DNA instructions for building the coronavirus’s spike protein to cells. There are few studies on J&J boosters, but the AstraZeneca vaccine, which is built on similar technology but not available in the United States, could provide some clues ( SN: 11/23/20 SN: 2/27/21). But a few months after the J&J shot, “it seems like your immune response is less protective.” “It doesn’t go away entirely,” says Sachin Nagrani, medical director of Heal, a company that provides primary health care in people’s homes via telehealth visits and house calls. That’s because the antibody response from that one-dose vaccine isn’t as high as for the two-dose mRNA vaccines from Pfizer and Moderna, and it is waning. health officials and experts say ( SN: 10/19/21).
Everyone who got that shot as their initial vaccine is recommended to get a booster two months after the first jab, U.S. What I found out could be useful to anyone deciding on a booster. But do I really need to get a third COVID-19 shot? If so, which of the three authorized or approved vaccines available in the United States should I get? To make my decision, I looked at the evidence and talked to some experts. It’s been a little over six months since I got my second dose of the COVID-19 vaccine from Pfizer and its German partner BioNTech, and a phone call from my state health department over the weekend reminded me that I am eligible for a booster.
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